| 1. | 7. | Boca Raton | Centennial | Haylee Mersereau, Likendia Dersire, Lauren Graham, Pia Beaulieu | Meily Ambrocio, Jessica Barrera-Solis, Ashlyn Mock, Adeilyn Volcanes | 55:09:45.8781 | 12:08.1361 | 0100 | - |
| 2. | | Park Vista | Deerfield Beach | Morgan Velazquez, Riley Phillips, Bre Pina, Justice Harvey | Meily Ambrocio, Jessica Barrera-Solis, Ashlyn Mock, Adeilyn Volcanes | 42:10:15.296 | 11:31.8711 | 884 | - |
| 3. | 14. | Spanish River | Jupiter | Victoria Siqueira, Zoe Pustilnik, Sarah Phillips, Amanda Veltri | Mackenzie Ramsey, Kimberly Fryar, Kammile Melandes, Kiana Vereen | 10:26.6037 | 20:11:10.731 | 3562 | 0100 |
| 4. | 10. | Jupiter | Wellington | Ava Romero, Sydney Buck, Alicia Gustafson, Elliana Manzo | Jenna Bojanowski, Shayna Thomas, Franceska Point-du-Jour, Starlia Dormeus | 7:10:29.2582 | DNS | 155 | 0100 |
| 5. | 15. | Palm Beach Central | Palm Beach Central | Catherine Lee, Yrlene Dorvil, Amanda Nunez, Runelda Jackson | Mackenzie Ramsey, Kimberly Fryar, Kammile Melandes, Kiana Vereen | 51:10:37.18 | 20:11:10.731 | 4478 | - |
| 6. | 5. | Martin County | Vero Beach | Ellen Diez, Anna Tullidge, Gina Fuca, Katherine Radcliff | Ellen Diez, Anna Tullidge, Gina Fuca, Katherine Radcliff | 50:10:44.967 | 58:12:39.8571 | 33 | 33 |
| 7. | 4. | Douglas | Martin County | Alyssa Fletcher, Emily Burke, Kayla Sanseverino, Gabriella Rumasuglia | Ellen Diez, Anna Tullidge, Gina Fuca, Katherine Radcliff | 10:55.616 | 55:09:45.8781 | 2 | - |
| 8. | 4. | Coral Springs | Martin County | Sara Castillo, Julia Fendell, Arianna Negron, Faith Cunningham | karen castro, mikayla herrington, Jurni Juergen, ta'niaya ferguson | 30:11:02.55 | 58:12:39.8571 | 8515 | - |
| 9. | 6. | John I. Leonard | Centennial | karen castro, mikayla herrington, Jurni Juergen, ta'niaya ferguson | Alyssa Fletcher, Emily Burke, Kayla Sanseverino, Gabriella Rumasuglia | 20:11:10.731 | 20:11:10.731 | - | - |
| 10. | | Fort Pierce Central | Jupiter | Mackenzie Ramsey, Kimberly Fryar, Kammile Melandes, Kiana Vereen | karen castro, mikayla herrington, Jurni Juergen, ta'niaya ferguson | 52:11:20.5940 | 58:12:39.8571 | - | - |
| 11. | | Vero Beach | Wellington | Nanci Pacheco, MengQi Chen, Sofia Rodriguez, Sydney Jones | Catherine Lee, Yrlene Dorvil, Amanda Nunez, Runelda Jackson | 36:11:26.4555 | 58:12:39.8571 | - | 33 |
| 12. | 11. | Monarch | John I. Leonard | Sarah Paul, J'Nay Thompson, Alysia Tigner, Quincy Ornus | Alyssa Fletcher, Emily Burke, Kayla Sanseverino, Gabriella Rumasuglia | 11:31.8711 | 36:11:26.4555 | - | 884 |
| 13. | 8. | Deerfield Beach | John I. Leonard | Adeline Appolon, Brianna Fisher, Annelise Kistner, Jasmine Worsely | Sarah Paul, J'Nay Thompson, Alysia Tigner, Quincy Ornus | 23:11:43.244 | 51:10:37.18 | - | 33 |
| 14. | 3. | Centennial | Deerfield Beach | Rolizbeth Acosta, Tindra Jofors, Ashlyn Lecrone, Kiara Badalo | Nanci Pacheco, MengQi Chen, Sofia Rodriguez, Sydney Jones | 12:08.1361 | 12:08.1361 | - | 4478 |
| 15. | 12. | Forest Hill | Centennial | Meily Ambrocio, Jessica Barrera-Solis, Ashlyn Mock, Adeilyn Volcanes | Nanci Pacheco, MengQi Chen, Sofia Rodriguez, Sydney Jones | 58:12:39.8571 | 12:08.1361 | - | - |
| | 1. | Wellington | Deerfield Beach | Jenna Bojanowski, Shayna Thomas, Franceska Point-du-Jour, Starlia Dormeus | Rolizbeth Acosta, Tindra Jofors, Ashlyn Lecrone, Kiara Badalo | DNS | 20:11:10.731 | - | 155 |
