| | 1. | 2. | Holy Names | Tampa Prep | Holy Names | Emily Rich, Molly Simmons, Kasey Singer, Keely Karnes | Kailyn Gilbert, Camille Samuel, Maggie Matulis, Summer Haura | Catelin Lipham, Carsyn Martz, Allison Holmes, Sydney Mercurio | 4:20.94 | 48:04:18.1974 | 4:31.9943 | 725 | 1028 | 725 |
| 3. | 2. | | Clearwater Central Catholic | Clearwater Central Catholic | Berkeley Prep | Camila Garanton, Sophie Haag, Stephanie Bainbridge, Jocelyn Chinea | Emily Rich, Molly Simmons, Kasey Singer, Keely Karnes | Catelin Lipham, Carsyn Martz, Allison Holmes, Sydney Mercurio | DQ | 4:20.94 | 4:31.9943 | 895 | 895 | 895 |
| 1. | 3. | 2. | Berkeley Prep | Carrollwood | Berkeley Prep | Greta Dieck, Alexa Fredericks, Madeline Rodriguez, Megan Hughes | Camila Garanton, Sophie Haag, Stephanie Bainbridge, Jocelyn Chinea | Emily Rich, Molly Simmons, Kasey Singer, Keely Karnes | 4:31.9943 | 31:04:24.791 | DQ | 725 | 596 | 596 |
| 2. | 4. | 2. | Berkeley Prep | Holy Names | Berkeley Prep | Greta Dieck, Alexa Fredericks, Madeline Rodriguez, Megan Hughes | Greta Dieck, Alexa Fredericks, Madeline Rodriguez, Megan Hughes | Greta Dieck, Alexa Fredericks, Madeline Rodriguez, Megan Hughes | 4:20.94 | 4:31.9943 | DQ | 596 | 725 | 596 |
| 1. | | | Holy Names | Berkeley Prep | Clearwater Central Catholic | Emily Rich, Molly Simmons, Kasey Singer, Keely Karnes | Catelin Lipham, Carsyn Martz, Allison Holmes, Sydney Mercurio | Emily Rich, Molly Simmons, Kasey Singer, Keely Karnes | 4:31.9943 | DQ | DQ | 895 | - | - |
